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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50016987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50016987
PNG
(7-Chloro-2-(4-methoxy-benzyl)-3,5-dipropyl-benzofu...)
Show SMILES CCCc1c(Cc2ccc(OC)cc2)oc2c(Cl)cc(CCC)c(O)c12
Show InChI InChI=1S/C22H25ClO3/c1-4-6-15-13-18(23)22-20(21(15)24)17(7-5-2)19(26-22)12-14-8-10-16(25-3)11-9-14/h8-11,13,24H,4-7,12H2,1-3H3
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Merck Frosst Canada Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compound


J Med Chem 32: 1190-7 (1989)


Article DOI: 10.1021/jm00126a008
BindingDB Entry DOI: 10.7270/Q2ST7NVR
More data for this
Ligand-Target Pair