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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50016990
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  12nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  140nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed