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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50024479   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50024479
PNG
((4-Chloro-phenyl)-cyclopropyl-pyrimidin-5-yl-metha...)
Show SMILES OC(C1CC1)(c1ccc(Cl)cc1)c1cncnc1
Show InChI InChI=1S/C14H13ClN2O/c15-13-5-3-11(4-6-13)14(18,10-1-2-10)12-7-16-9-17-8-12/h3-10,18H,1-2H2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.70E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.


J Med Chem 30: 1359-65 (1987)


Article DOI: 10.1021/jm00391a016
BindingDB Entry DOI: 10.7270/Q2NP251P
More data for this
Ligand-Target Pair