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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50024486   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50024486
PNG
(Bis-(4-chloro-phenyl)-(1-oxy-pyrimidin-5-yl)-metha...)
Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cnc[n+]([O-])c1
Show InChI InChI=1S/C17H12Cl2N2O2/c18-15-5-1-12(2-6-15)17(22,13-3-7-16(19)8-4-13)14-9-20-11-21(23)10-14/h1-11,22H
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>2.00E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.


J Med Chem 30: 1359-65 (1987)


Article DOI: 10.1021/jm00391a016
BindingDB Entry DOI: 10.7270/Q2NP251P
More data for this
Ligand-Target Pair