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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50024498   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50024498
PNG
(5-[1,1-Bis-(4-chloro-phenyl)-propyl]-pyrimidine | ...)
Show SMILES CCC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1
Show InChI InChI=1S/C19H16Cl2N2/c1-2-19(16-11-22-13-23-12-16,14-3-7-17(20)8-4-14)15-5-9-18(21)10-6-15/h3-13H,2H2,1H3
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PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.95E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.


J Med Chem 30: 1359-65 (1987)


Article DOI: 10.1021/jm00391a016
BindingDB Entry DOI: 10.7270/Q2NP251P
More data for this
Ligand-Target Pair