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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50024503   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50024503
PNG
(CHEMBL28860 | Cyclopropyl-pyrimidin-5-yl-thiophen-...)
Show SMILES OC(C1CC1)(c1cccs1)c1cncnc1
Show InChI InChI=1S/C12H12N2OS/c15-12(9-3-4-9,11-2-1-5-16-11)10-6-13-8-14-7-10/h1-2,5-9,15H,3-4H2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.


J Med Chem 30: 1359-65 (1987)


Article DOI: 10.1021/jm00391a016
BindingDB Entry DOI: 10.7270/Q2NP251P
More data for this
Ligand-Target Pair