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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50024524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50024524
PNG
(5-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyrimidine | C...)
Show SMILES CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1
Show InChI InChI=1S/C18H14Cl2N2/c1-18(15-10-21-12-22-11-15,13-2-6-16(19)7-3-13)14-4-8-17(20)9-5-14/h2-12H,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 82n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.


J Med Chem 30: 1359-65 (1987)


Article DOI: 10.1021/jm00391a016
BindingDB Entry DOI: 10.7270/Q2NP251P
More data for this
Ligand-Target Pair