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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50024986   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50024986
PNG
(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Show SMILES COc1noc2CC[NH+](Cc3ccccc3)Cc12
Show InChI InChI=1S/C14H16N2O2/c1-17-14-12-10-16(8-7-13(12)18-15-14)9-11-5-3-2-4-6-11/h2-6H,7-10H2,1H3/p+1
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Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropine


J Med Chem 29: 1004-9 (1986)


Article DOI: 10.1021/jm00156a018
BindingDB Entry DOI: 10.7270/Q2XP73XW
More data for this
Ligand-Target Pair