BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50029505   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasminogen


(Homo sapiens (Human))
BDBM50029505
PNG
(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Show SMILES CN[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@](C)(CCCNC(N)=N)C=O
Show InChI InChI=1S/C22H34N6O3/c1-22(15-29,11-7-12-26-21(23)24)27-19(30)18-10-6-13-28(18)20(31)17(25-2)14-16-8-4-3-5-9-16/h3-5,8-9,15,17-18,25H,6-7,10-14H2,1-2H3,(H,27,30)(H4,23,24,26)/t17-,18-,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.50E+5n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro Enzyme Inhibitory activity measured against Plasmin


J Med Chem 38: 4446-53 (1995)


Article DOI: 10.1021/jm00022a009
BindingDB Entry DOI: 10.7270/Q2RB73MV
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50029505
PNG
(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Show SMILES CN[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@](C)(CCCNC(N)=N)C=O
Show InChI InChI=1S/C22H34N6O3/c1-22(15-29,11-7-12-26-21(23)24)27-19(30)18-10-6-13-28(18)20(31)17(25-2)14-16-8-4-3-5-9-16/h3-5,8-9,15,17-18,25H,6-7,10-14H2,1-2H3,(H,27,30)(H4,23,24,26)/t17-,18-,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+7n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).


J Med Chem 38: 4446-53 (1995)


Article DOI: 10.1021/jm00022a009
BindingDB Entry DOI: 10.7270/Q2RB73MV
More data for this
Ligand-Target Pair