BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-1' and Monomerid = 50029609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1 (COX-1)


(Homo sapiens (Human))
BDBM50029609
PNG
(1,2-Dichloro-4-[2-(4-methanesulfonyl-phenyl)-cyclo...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C18H16Cl2O2S/c1-23(21,22)14-8-5-12(6-9-14)15-3-2-4-16(15)13-7-10-17(19)18(20)11-13/h5-11H,2-4H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of prostaglandin G/H synthase 1.


J Med Chem 38: 4570-8 (1995)


Article DOI: 10.1021/jm00022a023
BindingDB Entry DOI: 10.7270/Q23N22D2
More data for this
Ligand-Target Pair