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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-1' and Monomerid = 50029617   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1 (COX-1)


(Homo sapiens (Human))
BDBM50029617
PNG
(4-[2-(3,4-Difluoro-phenyl)-cyclopent-1-enyl]-benze...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C17H15F2NO2S/c18-16-9-6-12(10-17(16)19)15-3-1-2-14(15)11-4-7-13(8-5-11)23(20,21)22/h4-10H,1-3H2,(H2,20,21,22)
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Similars

Article
PubMed
n/an/a 8.10E+3n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of prostaglandin G/H synthase 1.


J Med Chem 38: 4570-8 (1995)


Article DOI: 10.1021/jm00022a023
BindingDB Entry DOI: 10.7270/Q23N22D2
More data for this
Ligand-Target Pair