Found 33 Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Monomerid = 50031467 
Affinity DataKi: 3.50E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of TyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.15E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Tyrosinase (unknown origin) using tyrosine as substrate incubated for 20 mins followed by substrate addition and measured every 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibitory activity against mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.29E+4nMAssay Description:Compound was evaluated for inhibition of tyrosinase enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-dihydroxyphenylalanine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of Bacillus megaterium tyrosinase diphenolase activity using L-DOPA as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+4nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.97E+4nMAssay Description:Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibitory activity against mushroom tyrosinase (approximate value given)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.71E+5nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+6nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+7nMAssay Description:Inhibition of zebrafish embryo tyrosinase assessed as melanin production after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+7nMAssay Description:Inhibition of zebrafish embryo tyrosinase assessed as residual activity after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+7nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
Affinity DataKd: 3.77E+5nMAssay Description:Binding affinity to Bacillus megaterium Tyrosinase expressed in Escherichia coli BL21 assessed as dissociation constant incubated for 5 mins by by Re...More data for this Ligand-Target Pair
