BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 Receptor' and Monomerid = 50040109   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50040109
PNG
(3-{11-[2-(4-Benzyl-piperidin-1-yl)-ethylsulfanyl]-...)
Show SMILES OC(=O)CCc1ccc2OCc3ccccc3C(SCCN3CCC(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1/C31H35NO3S/c33-30(34)13-11-24-10-12-29-28(21-24)31(27-9-5-4-8-26(27)22-35-29)36-19-18-32-16-14-25(15-17-32)20-23-6-2-1-3-7-23/h1-10,12,21,25,31H,11,13-20,22H2,(H,33,34)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [3H]-pyrilamine to guinea pig cerebellum histamine H1 receptor


J Med Chem 36: 417-20 (1993)


Article DOI: 10.1021/jm00055a013
BindingDB Entry DOI: 10.7270/Q2Q23Z9K
More data for this
Ligand-Target Pair