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Found 7 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Monomerid = 50041178
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50:  8.93E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041178(5-((3,4-dichlorophenylamino)methyl)furo[2,3-d]pyri...)
Affinity DataIC50:  8.93E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed