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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50042502
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042502(CHEMBL118493 | N-hydroxy-N'-tertbutyl-N-[(6-phenox...)
Affinity DataIC50:  4.40E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042502(CHEMBL118493 | N-hydroxy-N'-tertbutyl-N-[(6-phenox...)
Affinity DataIC50:  6.20E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed