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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50042517
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042517(CHEMBL118393 | N-(6-Cyclohexylmethoxy-2H-chromen-3...)
Affinity DataIC50:  1.36E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042517(CHEMBL118393 | N-(6-Cyclohexylmethoxy-2H-chromen-3...)
Affinity DataIC50:  1.39E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed