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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Monomerid = 50042838   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))
BDBM50042838
PNG
(6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotridecane...)
Show SMILES OC(=O)[C@@H]1CSCCCCCCCC(CS)C(=O)N1
Show InChI InChI=1S/C13H23NO3S2/c15-12-10(8-18)6-4-2-1-3-5-7-19-9-11(14-12)13(16)17/h10-11,18H,1-9H2,(H,14,15)(H,16,17)/t10?,11-/m0/s1
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MMDB

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Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Ciba-Geigy Corporation

Curated by ChEMBL


Assay Description
Tested in vitro for the inhibition against angiotensin converting enzyme (ACE) from rabbit lung


J Med Chem 36: 3829-33 (1994)


Article DOI: 10.1021/jm00076a010
BindingDB Entry DOI: 10.7270/Q2125RRG
More data for this
Ligand-Target Pair