BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50043678   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Mus musculus)
BDBM50043678
PNG
((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Show SMILES CC[C@@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1
Show InChI InChI=1S/C23H24FNO5/c1-5-23(29-4,22(27)28-3)17-11-18(24)13-19(12-17)30-14-15-6-8-20-16(10-15)7-9-21(26)25(20)2/h6-13H,5,14H2,1-4H3/t23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from mouse macrophage


J Med Chem 37: 113-24 (1994)


Article DOI: 10.1021/jm00027a014
BindingDB Entry DOI: 10.7270/Q2JW8CZP
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50043678
PNG
((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Show SMILES CC[C@@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1
Show InChI InChI=1S/C23H24FNO5/c1-5-23(29-4,22(27)28-3)17-11-18(24)13-19(12-17)30-14-15-6-8-20-16(10-15)7-9-21(26)25(20)2/h6-13H,5,14H2,1-4H3/t23-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Inhibitory concentration against 5-lipoxygenase from human whole blood


J Med Chem 37: 113-24 (1994)


Article DOI: 10.1021/jm00027a014
BindingDB Entry DOI: 10.7270/Q2JW8CZP
More data for this
Ligand-Target Pair