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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50045674
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045674(3-[1-(4-Chloro-benzyl)-4-methyl-6-(4-phenyl-pyridi...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045674(3-[1-(4-Chloro-benzyl)-4-methyl-6-(4-phenyl-pyridi...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed