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Found 7 Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor alpha' and Monomerid = 50052414
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50:  41nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataKd:  36nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataEC50:  2nMAssay Description:Effective concentration for retinoic acid receptor RAR gamma transcriptional activationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at RARalpha by TR-FRET assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataEC50:  0.300nMAssay Description:Activity at human RARalpha ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataEC50:  79.4nMAssay Description:Activity at RARalpha expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataKd:  36nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair