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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50053503
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053503(5-Methyl-1-(3-thiophen-2-yl-phenyl)-[1,2,4]triazin...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053503(5-Methyl-1-(3-thiophen-2-yl-phenyl)-[1,2,4]triazin...)
Affinity DataIC50:  5.50E+3nMAssay Description:In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed