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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50056765
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056765(CHEMBL166844 | N-hydroxy-N'-[1-(4-isobutylphenyl)e...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056765(CHEMBL166844 | N-hydroxy-N'-[1-(4-isobutylphenyl)e...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase in Human whole blood (HWBL) stimulated with calcium ionophore (A23187) and LTB4 measured by enzyme immunoa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed