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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50059718   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50059718
PNG
(4-Furan-3-yl-7-[7-(4-hydroxy-tetrahydro-pyran-4-yl...)
Show SMILES OC1(CCOCC1)c1ccc2ccc(COc3ccc4c(cc(cc4c3)C#N)-c3ccoc3)nc2c1
Show InChI InChI=1S/C30H24N2O4/c31-17-20-13-23-15-26(5-6-27(23)28(14-20)22-7-10-35-18-22)36-19-25-4-2-21-1-3-24(16-29(21)32-25)30(33)8-11-34-12-9-30/h1-7,10,13-16,18,33H,8-9,11-12,19H2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay


J Med Chem 40: 2866-75 (1997)


Article DOI: 10.1021/jm970046b
BindingDB Entry DOI: 10.7270/Q2QN67G4
More data for this
Ligand-Target Pair