Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50060719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50060719 ((S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...) Show SMILES Cc1o[nH]c(=O)c1CC[C@H](N)C(O)=O Show InChI InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t6-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).				J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50060719 ((S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...) Show SMILES Cc1o[nH]c(=O)c1CC[C@H](N)C(O)=O Show InChI InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t6-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2				J Med Chem 45: 4240-5 (2002) Article DOI: 10.1021/jm020122x BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50060719 ((S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...) Show SMILES Cc1o[nH]c(=O)c1CC[C@H](N)C(O)=O Show InChI InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t6-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 2				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
					More data for this Ligand-Target Pair