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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50062534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50062534
PNG
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-methoxy-phenyl)-...)
Show SMILES COc1cccc(CC[C@@](N)(C2C[C@@H]2C(O)=O)C(O)=O)c1
Show InChI InChI=1S/C15H19NO5/c1-21-10-4-2-3-9(7-10)5-6-15(16,14(19)20)12-8-11(12)13(17)18/h2-4,7,11-12H,5-6,8,16H2,1H3,(H,17,18)(H,19,20)/t11-,12?,15+/m0/s1
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Article
PubMed
n/an/a 430n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 2


J Med Chem 41: 358-78 (1998)


Article DOI: 10.1021/jm970498o
BindingDB Entry DOI: 10.7270/Q2XP7423
More data for this
Ligand-Target Pair