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Found 9 Enz. Inhib. hit(s) with Target = 'Complement C1r' and Monomerid = 50063698
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human serum C1r using AAME as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:The compound was evaluated to inhibit 50% of Clr Serine Protease after 60 mins and is expressed in IC50 (microM).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article