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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50063786   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50063786
PNG
(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Show SMILES CC(C)CCCC(=O)c1cc2c(OCC2(C)C)c(c1)C(C)(C)C
Show InChI InChI=1S/C21H32O2/c1-14(2)9-8-10-18(22)15-11-16(20(3,4)5)19-17(12-15)21(6,7)13-23-19/h11-12,14H,8-10,13H2,1-7H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested for the concentration (in microM) to inhibit 50% of 5-Lipoxygenase (5-LOX) and is expressed in IC50.


J Med Chem 41: 1112-23 (1998)


Article DOI: 10.1021/jm970679q
BindingDB Entry DOI: 10.7270/Q2K936N4
More data for this
Ligand-Target Pair