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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50064247   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50064247
PNG
((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Show SMILES N[C@]1(C[C@@H]2C[C@H]1[C@@H]2C(O)=O)C(O)=O
Show InChI InChI=1S/C8H11NO4/c9-8(7(12)13)2-3-1-4(8)5(3)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5+,8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.80E+4n/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).


J Med Chem 41: 1641-50 (1998)


Article DOI: 10.1021/jm970719q
BindingDB Entry DOI: 10.7270/Q27945BZ
More data for this
Ligand-Target Pair