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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50064850   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50064850
PNG
(CHEMBL268069 | Y-Pen-YGSFCKK-NH2)
Show SMILES CC(C)(S)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O
Show InChI InChI=1S/C52H76N12O12S2/c1-52(2,78)43(64-45(70)35(55)24-31-14-18-33(66)19-15-31)51(76)62-38(26-32-16-20-34(67)21-17-32)46(71)57-27-42(68)58-40(28-65)49(74)61-39(25-30-10-4-3-5-11-30)48(73)63-41(29-77)50(75)60-37(13-7-9-23-54)47(72)59-36(44(56)69)12-6-8-22-53/h3-5,10-11,14-21,35-41,43,65-67,77-78H,6-9,12-13,22-29,53-55H2,1-2H3,(H2,56,69)(H,57,71)(H,58,68)(H,59,72)(H,60,75)(H,61,74)(H,62,76)(H,63,73)(H,64,70)/t35-,36-,37-,38-,39-,40-,41-,43+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of c-Src tyrosine kinase.


J Med Chem 41: 2252-60 (1998)


Article DOI: 10.1021/jm9707885
BindingDB Entry DOI: 10.7270/Q24X56W6
More data for this
Ligand-Target Pair