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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50065838   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50065838
PNG
(CHEMBL538767 | N-[4-(2-Amino-ethyl)-phenyl]-acetam...)
Show SMILES CC(N)=Nc1ccc(CCN)cc1
Show InChI InChI=1S/C10H15N3/c1-8(12)13-10-4-2-9(3-5-10)6-7-11/h2-5H,6-7,11H2,1H3,(H2,12,13)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.30E+4n/an/an/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against human endothelial nitric oxide synthase (eNOS) isoenzyme.


J Med Chem 41: 2858-71 (1998)


Article DOI: 10.1021/jm980072p
BindingDB Entry DOI: 10.7270/Q2862H4X
More data for this
Ligand-Target Pair