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Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50066347   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50066347
PNG
(2-Morpholin-4-yl-N-[6-(2-morpholin-4-yl-acetylamin...)
Show SMILES O=C(CN1CCOCC1)Nc1ccc2C(=O)c3cc(NC(=O)CN4CCOCC4)ccc3C(=O)c2c1
Show InChI InChI=1S/C26H28N4O6/c31-23(15-29-5-9-35-10-6-29)27-17-1-3-19-21(13-17)26(34)20-4-2-18(14-22(20)25(19)33)28-24(32)16-30-7-11-36-12-8-30/h1-4,13-14H,5-12,15-16H2,(H,27,31)(H,28,32)
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity


J Med Chem 41: 3253-60 (1998)


Article DOI: 10.1021/jm9801105
BindingDB Entry DOI: 10.7270/Q2TX3G1R
More data for this
Ligand-Target Pair