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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50066368   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50066368
PNG
(CHEMBL419381 | N-[9,10-Dioxo-6-(2-piperidin-1-yl-a...)
Show SMILES O=C(CN1CCCCC1)Nc1ccc2C(=O)c3cc(NC(=O)CN4CCCCC4)ccc3C(=O)c2c1
Show InChI InChI=1S/C28H32N4O4/c33-25(17-31-11-3-1-4-12-31)29-19-7-9-21-23(15-19)27(35)22-10-8-20(16-24(22)28(21)36)30-26(34)18-32-13-5-2-6-14-32/h7-10,15-16H,1-6,11-14,17-18H2,(H,29,33)(H,30,34)
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity


J Med Chem 41: 3253-60 (1998)


Article DOI: 10.1021/jm9801105
BindingDB Entry DOI: 10.7270/Q2TX3G1R
More data for this
Ligand-Target Pair