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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50066777   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

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KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.29E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.12E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair