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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50068324   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50068324
PNG
(3-Dimethylamino-N-[5-(3-dimethylamino-propionylami...)
Show SMILES CN(C)CCC(=O)Nc1cccc2C(=O)c3c(NC(=O)CCN(C)C)cccc3C(=O)c12
Show InChI InChI=1S/C24H28N4O4/c1-27(2)13-11-19(29)25-17-9-5-7-15-21(17)23(31)16-8-6-10-18(22(16)24(15)32)26-20(30)12-14-28(3)4/h5-10H,11-14H2,1-4H3,(H,25,29)(H,26,30)
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Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity of telomerase was measured using the TRAP assay.


J Med Chem 41: 4873-84 (1998)


Article DOI: 10.1021/jm981067o
BindingDB Entry DOI: 10.7270/Q2WW7GSD
More data for this
Ligand-Target Pair