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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50068326   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50068326
PNG
(CHEMBL142900 | N-[9,10-Dioxo-5-(3-(N-methylmorphol...)
Show SMILES C[N+]1(CCC(=O)Nc2cccc3C(=O)c4c(NC(=O)CC[N+]5(C)CCOCC5)cccc4C(=O)c23)CCOCC1
Show InChI InChI=1S/C30H36N4O6/c1-33(13-17-39-18-14-33)11-9-25(35)31-23-7-3-5-21-27(23)29(37)22-6-4-8-24(28(22)30(21)38)32-26(36)10-12-34(2)15-19-40-20-16-34/h3-8H,9-20H2,1-2H3/p+2
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Similars

Article
PubMed
n/an/a 1.32E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity of telomerase was measured using the TRAP assay.


J Med Chem 41: 4873-84 (1998)


Article DOI: 10.1021/jm981067o
BindingDB Entry DOI: 10.7270/Q2WW7GSD
More data for this
Ligand-Target Pair