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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50068328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50068328
PNG
(CHEMBL144303 | N-[9,10-Dioxo-4-(3-(N,N-diethyl-N-m...)
Show SMILES CC[N+](C)(CC)CCC(=O)Nc1ccc(NC(=O)CC[N+](C)(CC)CC)c2C(=O)c3ccccc3C(=O)c12
Show InChI InChI=1S/C30H40N4O4/c1-7-33(5,8-2)19-17-25(35)31-23-15-16-24(32-26(36)18-20-34(6,9-3)10-4)28-27(23)29(37)21-13-11-12-14-22(21)30(28)38/h11-16H,7-10,17-20H2,1-6H3/p+2
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Similars

Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity of telomerase was measured using the TRAP assay.


J Med Chem 41: 4873-84 (1998)


Article DOI: 10.1021/jm981067o
BindingDB Entry DOI: 10.7270/Q2WW7GSD
More data for this
Ligand-Target Pair