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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase 12' and Monomerid = 50068850   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase 12


(Mus musculus)
BDBM50068850
PNG
((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-2...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](C1CCCC1)C(=O)NO
Show InChI InChI=1S/C21H26N2O5S/c1-28-18-11-13-19(14-12-18)29(26,27)23(15-16-7-3-2-4-8-16)20(21(24)22-25)17-9-5-6-10-17/h2-4,7-8,11-14,17,20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t20-/m1/s1
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Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Novartis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate


Bioorg Med Chem Lett 8: 897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00142-5
BindingDB Entry DOI: 10.7270/Q2NP24ZC
More data for this
Ligand-Target Pair