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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase 12' and Monomerid = 50068851   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase 12


(Mus musculus)
BDBM50068851
PNG
((2R,4S)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amin...)
Show SMILES CC[C@H](C)C[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO
Show InChI InChI=1S/C21H28N2O5S/c1-4-16(2)14-20(21(24)22-25)23(15-17-8-6-5-7-9-17)29(26,27)19-12-10-18(28-3)11-13-19/h5-13,16,20,25H,4,14-15H2,1-3H3,(H,22,24)/t16-,20+/m0/s1
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Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Novartis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate


Bioorg Med Chem Lett 8: 897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00142-5
BindingDB Entry DOI: 10.7270/Q2NP24ZC
More data for this
Ligand-Target Pair