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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase 12' and Monomerid = 50068852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase 12


(Mus musculus)
BDBM50068852
PNG
(CHEMBL265476 | {(R)-5-[Benzyl-(4-methoxy-benzenesu...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](CCCCNC(=O)Oc1ccccc1)C(=O)NO
Show InChI InChI=1S/C27H31N3O7S/c1-36-22-15-17-24(18-16-22)38(34,35)30(20-21-10-4-2-5-11-21)25(26(31)29-33)14-8-9-19-28-27(32)37-23-12-6-3-7-13-23/h2-7,10-13,15-18,25,33H,8-9,14,19-20H2,1H3,(H,28,32)(H,29,31)/t25-/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Novartis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate


Bioorg Med Chem Lett 8: 897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00142-5
BindingDB Entry DOI: 10.7270/Q2NP24ZC
More data for this
Ligand-Target Pair