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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50071154   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50071154
PNG
((2R,4R)-4-Amino-1-(3-phenyl-propyl)-pyrrolidine-2,...)
Show SMILES N[C@@]1(C[C@@H](N(CCCc2ccccc2)C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H20N2O4/c16-15(14(20)21)9-12(13(18)19)17(10-15)8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,16H2,(H,18,19)(H,20,21)/t12-,15-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.


Bioorg Med Chem Lett 8: 1985-90 (1999)


Article DOI: 10.1016/s0960-894x(98)00352-7
BindingDB Entry DOI: 10.7270/Q2K35V5D
More data for this
Ligand-Target Pair