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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50071166   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50071166
PNG
((2R,4R)-4-Amino-1-(3,3-diphenyl-propyl)-pyrrolidin...)
Show SMILES N[C@@]1(C[C@@H](N(CCC(c2ccccc2)c2ccccc2)C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C21H24N2O4/c22-21(20(26)27)13-18(19(24)25)23(14-21)12-11-17(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17-18H,11-14,22H2,(H,24,25)(H,26,27)/t18-,21-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.


Bioorg Med Chem Lett 8: 1985-90 (1999)


Article DOI: 10.1016/s0960-894x(98)00352-7
BindingDB Entry DOI: 10.7270/Q2K35V5D
More data for this
Ligand-Target Pair