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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50071178   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50071178
PNG
(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Show SMILES COc1ccc2C3Oc4ccc5[nH]c(C)cc5c4CN3CCc2c1
Show InChI InChI=1/C20H20N2O2/c1-12-9-16-17-11-22-8-7-13-10-14(23-2)3-4-15(13)20(22)24-19(17)6-5-18(16)21-12/h3-6,9-10,20-21H,7-8,11H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.15E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research

Curated by ChEMBL


Assay Description
Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamste...


Bioorg Med Chem Lett 8: 1991-6 (1999)


Article DOI: 10.1016/s0960-894x(98)00351-5
BindingDB Entry DOI: 10.7270/Q2FB53F2
More data for this
Ligand-Target Pair