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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H3 Receptor' and Monomerid = 50071197
TargetHistamine H3 receptor(Homo sapiens (Human))
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [125I]-iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  12nMAssay Description:Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  56nMAssay Description:In vitro Histamine H3 receptor antagonist activity in an assay with K+-evoked depolarization-induced release of [3H]-histamine from synaptosomes of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKd:  25.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed