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Found 3 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50072215
TargetMuscarinic acetylcholine receptor M2(RAT)
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Curated by ChEMBL
LigandPNGBDBM50072215(1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50072215(1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...)
Affinity DataEC50:  241nMAssay Description:Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072215(1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...)
Affinity DataEC50:  240nMAssay Description:Stimulation of cAMP in CHO cells expressing human m2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed