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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50076078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50076078
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,5-Dimethyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)NC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H38N2O2/c1-14-12-24(13-15(2)23-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)25/h14-21,23H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>500n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand


Bioorg Med Chem Lett 9: 901-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00101-8
BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair