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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50076476   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50076476
PNG
(1-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-cy...)
Show SMILES N[C@]1(C[C@@H](C1)n1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C7H9N3O5/c8-7(4(11)12)1-3(2-7)10-5(13)9-6(14)15-10/h3H,1-2,8H2,(H,11,12)(H,9,13,14)/t3-,7-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.90E+4n/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Compound was tested for the stimulation of Phosphoinositide (PI) hydrolysis in BHK cells expresssing mGluR5a receptor


J Med Chem 42: 1639-47 (1999)


Article DOI: 10.1021/jm9806897
BindingDB Entry DOI: 10.7270/Q2028QQF
More data for this
Ligand-Target Pair