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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50079134   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50079134
PNG
(CHEMBL329427 | N-{9-Oxo-7-[3-(4-pyrimidin-2-yl-pip...)
Show SMILES O=C(CCN1CCN(CC1)c1ncccn1)Nc1ccc2-c3ccc(NC(=O)CCN4CCN(CC4)c4ncccn4)cc3C(=O)c2c1
Show InChI InChI=1S/C35H38N10O3/c46-31(7-13-42-15-19-44(20-16-42)34-36-9-1-10-37-34)40-25-3-5-27-28-6-4-26(24-30(28)33(48)29(27)23-25)41-32(47)8-14-43-17-21-45(22-18-43)35-38-11-2-12-39-35/h1-6,9-12,23-24H,7-8,13-22H2,(H,40,46)(H,41,47)
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase


J Med Chem 42: 2679-84 (1999)


Article DOI: 10.1021/jm990084q
BindingDB Entry DOI: 10.7270/Q2DF6RX9
More data for this
Ligand-Target Pair