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Found 2 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50079150   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50079150
PNG
(3-trimethylammonium-N-[7-(3-trimethylammonium-prop...)
Show SMILES C[N+](C)(C)CCC(=O)Nc1ccc2-c3ccc(NC(=O)CC[N+](C)(C)C)cc3C(=O)c2c1
Show InChI InChI=1S/C25H32N4O3/c1-28(2,3)13-11-23(30)26-17-7-9-19-20-10-8-18(16-22(20)25(32)21(19)15-17)27-24(31)12-14-29(4,5)6/h7-10,15-16H,11-14H2,1-6H3/p+2
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KEGG

UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.85E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase


J Med Chem 42: 2679-84 (1999)


Article DOI: 10.1021/jm990084q
BindingDB Entry DOI: 10.7270/Q2DF6RX9
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50079150
PNG
(3-trimethylammonium-N-[7-(3-trimethylammonium-prop...)
Show SMILES C[N+](C)(C)CCC(=O)Nc1ccc2-c3ccc(NC(=O)CC[N+](C)(C)C)cc3C(=O)c2c1
Show InChI InChI=1S/C25H32N4O3/c1-28(2,3)13-11-23(30)26-17-7-9-19-20-10-8-18(16-22(20)25(32)21(19)15-17)27-24(31)12-14-29(4,5)6/h7-10,15-16H,11-14H2,1-6H3/p+2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 1.86E+10n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of telomerase (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair