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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50079151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50079151
PNG
(CHEMBL91106 | N-{9-Oxo-7-[3-(4-phenyl-piperazin-1-...)
Show SMILES O=C(CCN1CCN(CC1)c1ccccc1)Nc1ccc2-c3ccc(NC(=O)CCN4CCN(CC4)c4ccccc4)cc3C(=O)c2c1
Show InChI InChI=1S/C39H42N6O3/c46-37(15-17-42-19-23-44(24-20-42)31-7-3-1-4-8-31)40-29-11-13-33-34-14-12-30(28-36(34)39(48)35(33)27-29)41-38(47)16-18-43-21-25-45(26-22-43)32-9-5-2-6-10-32/h1-14,27-28H,15-26H2,(H,40,46)(H,41,47)
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase


J Med Chem 42: 2679-84 (1999)


Article DOI: 10.1021/jm990084q
BindingDB Entry DOI: 10.7270/Q2DF6RX9
More data for this
Ligand-Target Pair