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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Monomerid = 50079590   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50079590
PNG
((S)-3-(Pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptan...)
Show SMILES C1CN2CC1[C@@H](C2)Oc1cnccn1
Show InChI InChI=1S/C10H13N3O/c1-4-13-6-8(1)9(7-13)14-10-5-11-2-3-12-10/h2-3,5,8-9H,1,4,6-7H2/t8?,9-/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Affinity towards human M1 receptor expressed in CHO cells using [3H]QNB as radioligand


Bioorg Med Chem Lett 9: 1895-900 (1999)


Article DOI: 10.1016/s0960-894x(99)00313-3
BindingDB Entry DOI: 10.7270/Q2G161CX
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50079590
PNG
((S)-3-(Pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptan...)
Show SMILES C1CN2CC1[C@@H](C2)Oc1cnccn1
Show InChI InChI=1S/C10H13N3O/c1-4-13-6-8(1)9(7-13)14-10-5-11-2-3-12-10/h2-3,5,8-9H,1,4,6-7H2/t8?,9-/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.60E+3n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Affinity towards human M1 receptor expressed in CHO cells using [3H]QNB as radioligand


Bioorg Med Chem Lett 9: 1895-900 (1999)


Article DOI: 10.1016/s0960-894x(99)00313-3
BindingDB Entry DOI: 10.7270/Q2G161CX
More data for this
Ligand-Target Pair